Relatively Benign Sickle-cell Anaemia in 60 Patients Aged Over 30 in the West Indies

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Relatively benign sickle-cell anaemia in 60 patients aged over 30 in the West Indies.

A study in Jamaica of 60 patients with sickle-cell anaemia over the age of 30 years showed that most of them were in full-time employment. Pains in the bones or joints, leg ulceration, and jaundice were the most frequent types of presentation, but only two patients had a haemoglobin level consistently below 6 g./ 100 ml. Most of the patients were well developed and of average height, and, thoug...

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Sir,—We were very interested to read Dr. R. A. Browne's article on this subject (Brit. J. Anaesth. (1965), 37, 181) and feel that a case which we were requested to anaesthetize might be worthy of comment in this connection. The patient was a West Indian woman, age 27 years, gravida-4 with a long history of sickle-cell anaemia, for which she had received alkalis plus blood transfusions. She was ...

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Profile of the Nigerian sickle cell anaemia patients above 30 years of age.

OBJECTIVE To examine the haematological profiles of patients with sickle cell anaemia above the age of 30 years. DESIGN Prospective cross sectional study. SETTING Department of Haematology University College Hospital, Ibadan, Nigeria. SUBJECTS 98 patients with sickle cell anaemia above the age of 30 years. MAIN OUTCOME MEASURES Clinical and haematological profiles of the patients. RES...

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Effect of Lisinopril on Microalbuminuria in Sickle Cell Anaemia Children: A Single-Blind Randomized Controlled Trial

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Sickle Cell Disease and Sickle Cell Anaemia

Sickle cell haemoglobin (HbS) results from an autosomal recessively inherited mutation in which the 17th nucleotide of the beta globin gene is changed from thymine to adenine and the amino acid glutamic acid is replaced by valine at position 6 in the beta globin chain. [1, 2]Sickle cells have a reduced deformability and are easily destroyed, causing occlusion of the microcirculation and a chron...

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ژورنال

عنوان ژورنال: BMJ

سال: 1968

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.3.5610.86